GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Becn1 | affects methylation | ISO | BECN1 (Homo sapiens) | 6480464 | CTD | Arsenic affects the methylation of BECN1 gene | PMID:25304211 | Becn1 | multiple interactions | ISO | Becn1 (Rattus norvegicus) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of BECN1 protein; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein; Melatonin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 mRNA] | PMID:31844926 PMID:35598369 PMID:36822304 | Becn1 | multiple interactions | ISO | BECN1 (Homo sapiens) | 6480464 | CTD | [Palmitic Acid co-treated with Arsenic] affects the expression of BECN1 mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein; bafilomycin A1 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 protein] | PMID:32645460 PMID:33736254 | | ||||||||||||||||||||||
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