GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ret | increases activity | ISO | RET (Homo sapiens) | 6480464 | CTD | Arsenic results in increased activity of RET protein; Arsenic results in increased activity of RET protein alternative form | PMID:21195159 | Ret | multiple interactions | ISO | RET (Homo sapiens) | 6480464 | CTD | [Arsenic co-treated with RET protein alternative form] results in increased secretion of MMP2 protein alternative form; [Arsenic co-treated with RET protein] results in increased secretion of MMP2 protein alternative form; Arsenic promotes the reaction [RET protein alternative form binds to RET protein alternative form]; Cysteine inhibits the reaction [[Arsenic co-treated with RET protein] results in increased secretion of MMP2 protein alternative form] | PMID:21195159 | |
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