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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1amultiple interactionsEXP 6480464CTD4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1A protein]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1A proteinPMID:35993674
Il1adecreases expressionISOIL1A (Homo sapiens)6480464CTDArsenic results in decreased expression of IL1A mRNAPMID:16835338
Il1aincreases expressionISOIL1A (Homo sapiens)6480464CTDArsenic results in increased expression of IL1A mRNAPMID:19945496 PMID:33736254
Il1amultiple interactionsISOIL1A (Homo sapiens)6480464CTD[Palmitic Acid co-treated with Arsenic] results in increased expression of IL1A mRNAPMID:33736254
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