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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2287
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cbs
Name: cystathionine beta synthase
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cbsaffects metabolic processingISOCBS (Homo sapiens)6480464CTDCBS gene polymorphism affects the metabolism of Arsenic; CBS gene SNP affects the metabolism of ArsenicPMID:20600216 PMID:20670920
Cbsaffects methylationISOCBS (Homo sapiens)6480464CTDArsenic affects the methylation of CBS genePMID:25304211
Cbsaffects response to substanceISOCBS (Homo sapiens)6480464CTDCBS gene polymorphism affects the susceptibility to ArsenicPMID:20670920
Cbsincreases expressionISOCBS (Homo sapiens)6480464CTDArsenic results in increased expression of CBS mRNAPMID:18487201
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