GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | decreases expression | EXP | | 6480464 | CTD | Arsenic results in decreased expression of BAX protein | PMID:11756236 | Bax | multiple interactions | EXP | | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; Succimer inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX protein] | PMID:30835071 PMID:32402895 PMID:36822304 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Arsenic results in increased expression of BAX protein | PMID:27289040 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Arsenic results in increased expression of BAX mRNA | PMID:29864498 PMID:30081983 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in increased expression of BAX mRNA]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA; [Sodium Fluoride results in increased abundance of Fluorides] promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA] | PMID:35714946 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in decreased expression of BAX protein; [Palmitic Acid co-treated with Arsenic] affects the expression of BAX mRNA | PMID:32802178 PMID:33736254 | |
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