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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Acc ID: CHEBI:47105
Term: 1-bromopropane
Definition: A bromoalkane that is propane carrying a bromo substituent at position 1.
Chemical ID: MESH:C118559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdnfdecreases expressionEXP 6480464CTD1-bromopropane results in decreased expression of BDNF mRNAPMID:23266320
Bdnfdecreases expressionISOBdnf (Mus musculus)6480464CTD1-bromopropane results in decreased expression of BDNF mRNAPMID:19189864
Bdnfdecreases expressionISOBDNF (Homo sapiens)6480464CTD1-bromopropane results in decreased expression of BDNF mRNAPMID:19189864
Bdnfmultiple interactionsISOBdnf (Mus musculus)6480464CTD1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]PMID:19189864
Bdnfmultiple interactionsISOBDNF (Homo sapiens)6480464CTD1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF mRNA]; 1-bromopropane inhibits the reaction [Colforsin results in increased expression of BDNF protein]PMID:19189864
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