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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737312
Species: Homo sapiens
RGD Object: Gene
Symbol: AGER
Name: advanced glycosylation end-product specific receptor
Acc ID: CHEBI:47013
Term: D-ribofuranose
Definition: A ribofuranose having D-configuration.
Chemical ID: MESH:D012266
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AGERincreases expressionISOAger (Mus musculus)6480464CTDRibose results in increased expression of AGER proteinPMID:30101366
AGERmultiple interactionsISOAger (Mus musculus)6480464CTD[Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]PMID:30101366
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