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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620525
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcl1
Name: MCL1 apoptosis regulator, BCL2 family member
Acc ID: CHEBI:46979
Term: N-acetylsphingosine
Definition: A N-acylsphingosine that has an acetamido group at position 2.
Chemical ID: MESH:C064769
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcl1increases degradationISORGD:7355126480464CTDN-acetylsphingosine results in increased degradation of MCL1 protein

PMID:21821001
Mcl1multiple interactionsISORGD:7355126480464CTDLGALS3 inhibits the reaction [N-acetylsphingosine results in increased degradation of MCL1 protein]

PMID:21821001
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