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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2965
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdr
Name: kinase insert domain receptor
Acc ID: CHEBI:46979
Term: N-acetylsphingosine
Definition: A N-acylsphingosine that has an acetamido group at position 2.
Chemical ID: MESH:C064769
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdrmultiple interactionsISORGD:108366480464CTDN-acetylsphingosine results in decreased phosphorylation of and results in decreased activity of KDR protein

PMID:15313899
Kdrmultiple interactionsISORGD:7310186480464CTDsphingosine 1-phosphate inhibits the reaction [N-acetylsphingosine results in decreased expression of KDR mRNA]

PMID:15741222
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