GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PARP1 | increases activity | EXP | | 6480464 | CTD | phytosphingosine results in increased activity of PARP1 protein | PMID:15486061 | PARP1 | increases cleavage | EXP | | 6480464 | CTD | phytosphingosine results in increased cleavage of PARP1 protein | PMID:37956922 | PARP1 | multiple interactions | EXP | | 6480464 | CTD | 3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]; [Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein; [Arsenic Trioxide co-treated with phytosphingosine] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein] | PMID:17237268 | | ||||||||||||||||||||||
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