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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319072
Species: Homo sapiens
RGD Object: Gene
Symbol: PRKDC
Name: protein kinase, DNA-activated, catalytic subunit
Acc ID: CHEBI:46680
Term: serpentine asbestos
Definition: null
Chemical ID: MESH:D017632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKDCmultiple interactionsISOPrkdc (Mus musculus)6480464CTDPRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL2 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL3 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL5 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CSF2 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CXCL1 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL10 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL13 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL4 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL5 protein]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of IL4 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MKI67 protein]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]PMID:16571779 PMID:17200189
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