Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	732911
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Cdkn1a
Name:	cyclin dependent kinase inhibitor 1A

Acc ID:	CHEBI:46678
Term:	amosite asbestos
Definition:	null
Chemical ID:	MESH:D017639

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Cdkn1a	decreases methylation	ISO	CDKN1A (Homo sapiens)	6480464	CTD	Asbestos, Amosite results in decreased methylation of CDKN1A gene	PMID:30990028

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.