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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732969
Species: Mus musculus
RGD Object: Gene
Symbol: Xrcc1
Name: X-ray repair complementing defective repair in Chinese hamster cells 1
Acc ID: CHEBI:46677
Term: amphibole asbestos
Definition: A class of asbestos minerals that includes silicates of magnesium, iron, calcium, and sodium.
Chemical ID: MESH:D017636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xrcc1decreases expressionISOXRCC1 (Homo sapiens)6480464CTDAsbestos, Amphibole results in decreased expression of XRCC1 proteinPMID:20855422
Xrcc1decreases response to substanceISOXRCC1 (Homo sapiens)6480464CTDXRCC1 results in decreased susceptibility to Asbestos, AmphibolePMID:20705543
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