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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:46677
Term: amphibole asbestos
Definition: A class of asbestos minerals that includes silicates of magnesium, iron, calcium, and sodium.
Chemical ID: MESH:D017636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3decreases expressionEXP 6480464CTDAsbestos, Amphibole results in decreased expression of NLRP3 mRNAPMID:27083413
Nlrp3increases expressionEXP 6480464CTDAsbestos, Amphibole results in increased expression of NLRP3 mRNAPMID:22168577
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