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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11429
Species: Mus musculus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:46677
Term: amphibole asbestos
Definition: A class of asbestos minerals that includes silicates of magnesium, iron, calcium, and sodium.
Chemical ID: MESH:D017636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfincreases expressionEXP 6480464CTDAsbestos, Amphibole results in increased expression of TNF proteinPMID:28870655
Tnfincreases expressionISOTNF (Homo sapiens)6480464CTDAsbestos, Amphibole results in increased expression of TNF mRNA; Asbestos, Amphibole results in increased expression of TNF proteinPMID:20855422 PMID:24401117
Tnfincreases expressionISOTnf (Rattus norvegicus)6480464CTDAsbestos, Amphibole results in increased expression of TNF mRNA; Asbestos, Amphibole results in increased expression of TNF proteinPMID:27083413
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