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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:46666
Term: crocidolite asbestos
Definition: null
Chemical ID: MESH:D017638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDAsbestos, Crocidolite results in increased expression of HMOX1 mRNA, Asbestos, Crocidolite results in increased expression of HMOX1 protein

PMID:15814490, PMID:17365036, PMID:7743507
increases expressionISORGD:107176480464CTDAsbestos, Crocidolite results in increased expression of HMOX1 mRNA, Asbestos, Crocidolite results in increased expression of HMOX1 protein

PMID:26938529
increases expressionISORGD:7309016480464CTDAsbestos, Crocidolite results in increased expression of HMOX1 mRNA, Asbestos, Crocidolite results in increased expression of HMOX1 protein

PMID:17365036, PMID:18687144, PMID:20831825, PMID:25757056
multiple interactionsISORGD:107176480464CTDsecoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of HMOX1 mRNA], secoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of HMOX1 protein]

PMID:26938529
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.