GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | RHOA | decreases prenylation | EXP | | 6480464 | CTD | Asbestos, Crocidolite results in decreased prenylation of RHOA protein | PMID:21257924 | RHOA | multiple interactions | EXP | | 6480464 | CTD | Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]; Asbestos, Crocidolite results in decreased activity of and results in decreased lipidation of RHOA protein; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased lipidation of RHOA protein]; tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Asbestos, Crocidolite results in decreased prenylation of RHOA protein] | PMID:17322126 PMID:21257924 | |
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