GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL1RN | increases expression | EXP | | 6480464 | CTD | Asbestos, Crocidolite results in increased expression of IL1RN mRNA | PMID:24160326 PMID:25351596 | IL1RN | multiple interactions | EXP | | 6480464 | CTD | [TNF protein co-treated with Asbestos, Crocidolite] results in increased secretion of IL1RN protein; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL18 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein]; IL1RN protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of FGF2 protein] | PMID:23937860 PMID:28056339 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |