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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620283
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxo1
Name: forkhead box O1
Acc ID: CHEBI:46661
Term: asbestos
Definition: Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements.
Chemical ID: MESH:D001194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxo1decreases expressionISOFOXO1 (Homo sapiens)6480464CTDAsbestos results in decreased expression of FOXO1 mRNAPMID:27042963
Foxo1multiple interactionsISOFOXO1 (Homo sapiens)6480464CTD[Asbestos results in decreased expression of FOXO1 mRNA] which results in decreased susceptibility to AsbestosPMID:27042963
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