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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2606
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf10
Name: fibroblast growth factor 10
Acc ID: CHEBI:46661
Term: asbestos
Definition: Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements.
Chemical ID: MESH:D001194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf10multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]]; FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]; U 0126 inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]]PMID:15618436
Fgf10decreases expressionISOFGF10 (Homo sapiens)6480464CTDAsbestos results in decreased expression of FGF10 mRNAPMID:22076105
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