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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733315
Species: Mus musculus
RGD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:46557
Term: zoledronic acid
Definition: An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.
Chemical ID: MESH:C088658
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2multiple interactionsISOIL2 (Homo sapiens)6480464CTDIL2 protein affects the reaction [zoledronic acid affects the expression of GZMB mRNA]; zoledronic acid promotes the reaction [IL2 protein affects the expression of IFNG protein]PMID:19400555 PMID:19446661
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