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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61834
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fdft1
Name: farnesyl diphosphate farnesyl transferase 1
Acc ID: CHEBI:46557
Term: zoledronic acid
Definition: An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.
Chemical ID: MESH:C088658
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fdft1increases expressionEXP 6480464CTDzoledronic acid results in increased expression of FDFT1 mRNAPMID:18325729
Fdft1multiple interactionsISOFDFT1 (Homo sapiens)6480464CTD[zoledronic acid co-treated with fluvastatin] results in increased expression of FDFT1 mRNAPMID:16996129
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