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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733710
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC22A5
Name: solute carrier family 22 member 5
Acc ID: CHEBI:4636
Term: diphenhydramine
Definition: An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
Chemical ID: MESH:D004155
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC22A5multiple interactionsISOSlc22a5 (Mus musculus)6480464CTDDiphenhydramine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]PMID:19821448
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