GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | BID | decreases expression | EXP | | 6480464 | CTD | Fluorouracil results in decreased expression of BID protein | PMID:15754201 | BID | decreases response to substance | EXP | | 6480464 | CTD | BID protein mutant form results in decreased susceptibility to Fluorouracil | PMID:15095271 | BID | increases response to substance | EXP | | 6480464 | CTD | BID protein results in increased susceptibility to Fluorouracil | PMID:15289866 | BID | multiple interactions | EXP | | 6480464 | CTD | [Fluorouracil co-treated with irinotecan co-treated with vorinostat] results in increased cleavage of BID protein; BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]; Fluorouracil results in increased cleavage of and results in increased activity of BID protein; IFNA1 promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of BID protein] | PMID:15289866 PMID:15754201 PMID:21474236 | BID | increases expression | ISO | Bid (Mus musculus) | 6480464 | CTD | Fluorouracil results in increased expression of BID protein | PMID:32270916 | BID | multiple interactions | ISO | Bid (Mus musculus) | 6480464 | CTD | casticin inhibits the reaction [Fluorouracil results in increased expression of BID protein] | PMID:32270916 | | ||||||||||||||||||||||
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