GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | decreases activity | EXP | | 6480464 | CTD | Diosgenin results in decreased activity of TNF protein | PMID:16331273 | TNF | multiple interactions | EXP | | 6480464 | CTD | Diosgenin inhibits the reaction [TNF protein results in increased activity of AKT1 protein] Diosgenin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] Diosgenin inhibits the reaction [TNF protein results in increased activity of RELA protein] Diosgenin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of BCL2 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of BCL2A1 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of CCND1 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of CFLAR protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of MMP9 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of MYC protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein] Diosgenin inhibits the reaction [TNF protein results in increased expression of VEGFA protein] Diosgenin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein] Diosgenin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] | PMID:16331273 | | ||||||||||||||||||||||
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