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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309780
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Car1
Name: carbonic anhydrase 1
Acc ID: CHEBI:46261
Term: N-phenylthiourea
Definition: A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing.
Chemical ID: MESH:D010670
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityISORGD:13203026480464CTDPhenylthiourea analog results in decreased activity of CA1 protein

PMID:30291660
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