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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735261
Species: Mus musculus
RGD Object: Gene
Symbol: Ces1d
Name: carboxylesterase 1D
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ces1daffects expressionEXP 6480464CTDAcetaminophen affects the expression of CES1D mRNAPMID:17562736
Ces1ddecreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of CES1D mRNAPMID:29246445
Ces1dmultiple interactionsEXP 6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of CES1D mRNA; PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of CES1D mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CES1D mRNA]PMID:17585979 PMID:29246445
Ces1ddecreases expressionISOCES1 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of CES1 mRNAPMID:26690555
Ces1dincreases expressionISOCES1 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of CES1 mRNAPMID:21163907 PMID:22230336
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