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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70999
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Decr1
Name: 2,4-dienoyl-CoA reductase 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Decr1decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of DECR1 mRNAPMID:33387578
Decr1affects expressionISODecr1 (Mus musculus)6480464CTDAcetaminophen affects the expression of DECR1 mRNAPMID:17562736
Decr1decreases expressionISODECR1 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of DECR1 mRNAPMID:25704631 PMID:29067470
Decr1multiple interactionsISODecr1 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of DECR1 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of DECR1 mRNA]PMID:17585979
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