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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70971
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hamp
Name: hepcidin antimicrobial peptide
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hampdecreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of HAMP mRNAPMID:32479839
Hampdecreases secretionEXP 6480464CTDAcetaminophen results in decreased secretion of HAMP proteinPMID:24038040
Hampdecreases expressionISOHamp (Mus musculus)6480464CTDAcetaminophen results in decreased expression of HAMP mRNAPMID:22610607
Hampdecreases expressionISOHAMP (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of HAMP mRNAPMID:29067470
Hampincreases expressionISOHAMP (Homo sapiens)6480464CTDAcetaminophen results in increased expression of HAMP mRNAPMID:22230336
Hampmultiple interactionsISOHamp (Mus musculus)6480464CTD[Acetaminophen results in decreased expression of HAMP mRNA] which results in increased abundance of IronPMID:22610607
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