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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70927
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mgst1
Name: microsomal glutathione S-transferase 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mgst1decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of MGST1 mRNAPMID:33387578
Mgst1affects expressionISOMgst1 (Mus musculus)6480464CTDAcetaminophen affects the expression of MGST1 mRNAPMID:17562736
Mgst1affects expressionISOMGST1 (Homo sapiens)6480464CTDAcetaminophen affects the expression of MGST1 mRNAPMID:25704631
Mgst1decreases expressionISOMgst1 (Mus musculus)6480464CTDAcetaminophen results in decreased expression of MGST1 proteinPMID:21329376
Mgst1decreases expressionISOMGST1 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of MGST1 mRNAPMID:11793227 PMID:29067470
Mgst1multiple interactionsISOMgst1 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of MGST1 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MGST1 mRNA]PMID:17585979
Mgst1multiple interactionsISOMGST1 (Homo sapiens)6480464CTD[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of MGST1 mRNAPMID:33819548
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