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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69038
Species: Homo sapiens
RGD Object: Gene
Symbol: IGFBP1
Name: insulin like growth factor binding protein 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IGFBP1increases expressionEXP 6480464CTDAcetaminophen results in increased expression of IGFBP1 mRNAPMID:11793227 PMID:29067470
IGFBP1multiple interactionsEXP 6480464CTD[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of IGFBP1 mRNAPMID:33819548
IGFBP1affects expressionISOIgfbp1 (Mus musculus)6480464CTDAcetaminophen affects the expression of IGFBP1 mRNAPMID:15606129 PMID:17562736
IGFBP1increases expressionISOIgfbp1 (Rattus norvegicus)6480464CTDAcetaminophen results in increased expression of IGFBP1 mRNAPMID:15120968 PMID:17202762 PMID:17522070
IGFBP1increases expressionISOIgfbp1 (Mus musculus)6480464CTDAcetaminophen results in increased expression of IGFBP1 mRNAPMID:17585979
IGFBP1multiple interactionsISOIgfbp1 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of IGFBP1 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IGFBP1 mRNA]PMID:17585979
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