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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69009
Species: Mus musculus
RGD Object: Gene
Symbol: Il13
Name: interleukin 13
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il13decreases response to substanceEXP 6480464CTDIL13 protein results in decreased susceptibility to AcetaminophenPMID:17439248
Il13increases expressionEXP 6480464CTDAcetaminophen results in increased expression of IL13 proteinPMID:11826401 PMID:17439248
Il13increases response to substanceEXP 6480464CTDIL13 gene mutant form results in increased susceptibility to AcetaminophenPMID:22107450
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