Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	68592
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	DBT
Name:	dihydrolipoamide branched chain transacylase E2

Acc ID:	CHEBI:46195
Term:	paracetamol
Definition:	A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID:	MESH:D000082

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
DBT	decreases expression	EXP		6480464	CTD	Acetaminophen results in decreased expression of DBT mRNA	PMID:29067470
DBT	increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DBT mRNA	PMID:22230336
DBT	affects expression	ISO	Dbt (Mus musculus)	6480464	CTD	Acetaminophen affects the expression of DBT mRNA	PMID:17562736
DBT	increases expression	ISO	Dbt (Rattus norvegicus)	6480464	CTD	Acetaminophen results in increased expression of DBT mRNA	PMID:33387578
DBT	multiple interactions	ISO	Dbt (Mus musculus)	6480464	CTD	[Clofibrate co-treated with Acetaminophen] affects the expression of DBT mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of DBT mRNA]	PMID:17585979

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