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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621675
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Timp1
Name: TIMP metallopeptidase inhibitor 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Timp1increases expressionEXP 6480464CTDAcetaminophen results in increased expression of TIMP1 proteinPMID:16687475
Timp1affects expressionISOTimp1 (Mus musculus)6480464CTDAcetaminophen affects the expression of TIMP1 mRNAPMID:17562736
Timp1increases expressionISOTIMP1 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of TIMP1 mRNAPMID:22230336
Timp1increases expressionISOTimp1 (Mus musculus)6480464CTDAcetaminophen results in increased expression of TIMP1 mRNAPMID:28286204
Timp1multiple interactionsISOTimp1 (Mus musculus)6480464CTDEGR1 protein affects the reaction [Acetaminophen results in increased expression of TIMP1 mRNA]PMID:28286204
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