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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61912
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc6a6
Name: solute carrier family 6 member 6
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of SLC6A6 mRNA

PMID:17202762, PMID:30723492
affects expressionISORGD:622056480464CTDAcetaminophen affects the expression of SLC6A6 mRNA

PMID:17562736
increases expressionISORGD:690046480464CTDAcetaminophen results in increased expression of SLC6A6 mRNA

PMID:29067470
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.