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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh3a2
Name: aldehyde dehydrogenase 3 family, member A2
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh3a2decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of ALDH3A2 mRNAPMID:17522070
Aldh3a2affects expressionISOAldh3a2 (Mus musculus)6480464CTDAcetaminophen affects the expression of ALDH3A2 mRNAPMID:17562736
Aldh3a2decreases expressionISOAldh3a2 (Mus musculus)6480464CTDAcetaminophen results in decreased expression of ALDH3A2 mRNAPMID:29246445
Aldh3a2decreases expressionISOALDH3A2 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of ALDH3A2 mRNAPMID:21420995 PMID:25704631 PMID:29067470
Aldh3a2multiple interactionsISOAldh3a2 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of ALDH3A2 mRNA; PANX1 gene mutant form promotes the reaction [Acetaminophen results in decreased expression of ALDH3A2 mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ALDH3A2 mRNA]PMID:17585979 PMID:29246445
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