GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcr2 | decreases expression | EXP | | 6480464 | CTD | Acetaminophen results in decreased expression of CXCR2 mRNA | PMID:33387578 | Cxcr2 | affects expression | ISO | Cxcr2 (Mus musculus) | 6480464 | CTD | Acetaminophen affects the expression of CXCR2 mRNA | PMID:17562736 | Cxcr2 | affects response to substance | ISO | Cxcr2 (Mus musculus) | 6480464 | CTD | CXCR2 protein affects the susceptibility to Acetaminophen | PMID:16552707 | Cxcr2 | increases expression | ISO | Cxcr2 (Mus musculus) | 6480464 | CTD | [Acetaminophen results in increased expression of CXCL10 protein] which results in increased expression of CXCR2 protein; Acetaminophen results in increased expression of CXCR2 mRNA; Acetaminophen results in increased expression of CXCR2 protein | PMID:11739529 PMID:31444509 PMID:34724096 | Cxcr2 | multiple interactions | ISO | Cxcr2 (Mus musculus) | 6480464 | CTD | Clodronic Acid inhibits the reaction [Acetaminophen results in increased expression of CXCR2 protein]; CXCR2 protein affects the reaction [Acetaminophen results in increased expression of HMOX1 mRNA]; CXCR2 protein affects the reaction [Acetaminophen results in increased expression of NOS2 mRNA]; IL10 protein inhibits the reaction [Clodronic Acid inhibits the reaction [Acetaminophen results in increased expression of CXCR2 protein]]; PTGES2 protein affects the reaction [Acetaminophen results in increased expression of CXCR2 mRNA] | PMID:16552707 PMID:31444509 PMID:34724096 | |
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