Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1623316
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp4a12b
Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4a12bdecreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of CYP4A12B mRNAPMID:29246445
Cyp4a12bmultiple interactionsEXP 6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of CYP4A12B mRNA; PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of CYP4A12B mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP4A12B mRNA]PMID:17585979 PMID:29246445
Cyp4a12bincreases expressionISOCyp4a1 (Rattus norvegicus)6480464CTDAcetaminophen results in increased expression of CYP4A1 mRNAPMID:18246545 PMID:32479839
Go Back to source page   Continue to Ontology report