GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp4a12b | decreases expression | EXP | | 6480464 | CTD | Acetaminophen results in decreased expression of CYP4A12B mRNA | PMID:29246445 | Cyp4a12b | multiple interactions | EXP | | 6480464 | CTD | [Clofibrate co-treated with Acetaminophen] affects the expression of CYP4A12B mRNA; PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of CYP4A12B mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP4A12B mRNA] | PMID:17585979 PMID:29246445 | Cyp4a12b | increases expression | ISO | Cyp4a1 (Rattus norvegicus) | 6480464 | CTD | Acetaminophen results in increased expression of CYP4A1 mRNA | PMID:18246545 PMID:32479839 | |
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