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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1598310
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rrm2
Name: ribonucleotide reductase regulatory subunit M2
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rrm2decreases expressionISORrm2 (Mus musculus)6480464CTDAcetaminophen results in decreased expression of RRM2 mRNAPMID:17942131
Rrm2decreases expressionISORRM2 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of RRM2 mRNAPMID:29067470
Rrm2increases expressionISORrm2 (Mus musculus)6480464CTDAcetaminophen results in increased expression of RRM2 mRNAPMID:24126418
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