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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553522
Species: Mus musculus
RGD Object: Gene
Symbol: Havcr1
Name: hepatitis A virus cellular receptor 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Havcr1affects expressionEXP 6480464CTDAcetaminophen affects the expression of HAVCR1 mRNAPMID:17562736
Havcr1increases expressionEXP 6480464CTDAcetaminophen results in increased expression of HAVCR1 mRNAPMID:30099449
Havcr1multiple interactionsEXP 6480464CTDRotenone inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 mRNA]PMID:30099449
Havcr1decreases expressionISOHAVCR1 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of HAVCR1 mRNAPMID:26690555
Havcr1increases expressionISOHavcr1 (Rattus norvegicus)6480464CTDAcetaminophen results in increased expression of HAVCR1 mRNA; Acetaminophen results in increased expression of HAVCR1 proteinPMID:22093918 PMID:35020164
Havcr1multiple interactionsISOHavcr1 (Rattus norvegicus)6480464CTD[boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 mRNA]; Hesperidin inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein]PMID:22093918 PMID:35020164
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