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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352480
Species: Homo sapiens
RGD Object: Gene
Symbol: NDUFA4
Name: NDUFA4 mitochondrial complex associated
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NDUFA4decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of NDUFA4 mRNAPMID:31059760
NDUFA4multiple interactionsEXP 6480464CTD[Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of NDUFA4 mRNAPMID:31059760
NDUFA4increases expressionISONdufa4 (Mus musculus)6480464CTDAcetaminophen results in increased expression of NDUFA4 proteinPMID:21329376
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