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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349615
Species: Homo sapiens
RGD Object: Gene
Symbol: PECAM1
Name: platelet and endothelial cell adhesion molecule 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PECAM1decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of PECAM1 mRNAPMID:21420995
PECAM1affects expressionISOPecam1 (Mus musculus)6480464CTDAcetaminophen affects the expression of PECAM1 mRNAPMID:17562736
PECAM1increases expressionISOPecam1 (Mus musculus)6480464CTDAcetaminophen results in increased expression of PECAM1 mRNA; Acetaminophen results in increased expression of PECAM1 proteinPMID:16565415 PMID:21135413
PECAM1multiple interactionsISOPecam1 (Mus musculus)6480464CTDFLT1 protein affects the reaction [Acetaminophen results in increased expression of PECAM1 mRNA]; Semaxinib inhibits the reaction [Acetaminophen results in increased expression of PECAM1 protein]PMID:16565415 PMID:21135413
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