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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348100
Species: Homo sapiens
RGD Object: Gene
Symbol: SP100
Name: SP100 nuclear antigen
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SP100decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of SP100 mRNAPMID:21420995 PMID:29067470
SP100increases expressionEXP 6480464CTDAcetaminophen results in increased expression of SP100 mRNAPMID:26690555
SP100decreases expressionISOSp100 (Rattus norvegicus)6480464CTDAcetaminophen results in decreased expression of SP100 mRNAPMID:33387578
SP100multiple interactionsISOSp100 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of SP100 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SP100 mRNA]PMID:17585979
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