GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | UGT1A10 | increases glucuronidation | EXP | | 6480464 | CTD | UGT1A10 protein results in increased glucuronidation of Acetaminophen | PMID:15117964 PMID:17898154 | UGT1A10 | decreases expression | ISO | Ugt1a10 (Mus musculus) | 6480464 | CTD | Acetaminophen results in decreased expression of UGT1A10 mRNA | PMID:23333575 PMID:26772156 | UGT1A10 | multiple interactions | ISO | Ugt1a10 (Mus musculus) | 6480464 | CTD | Genistein inhibits the reaction [Acetaminophen results in decreased expression of UGT1A10 mRNA]; hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A10 mRNA] | PMID:23333575 PMID:26772156 | |
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