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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345394
Species: Homo sapiens
RGD Object: Gene
Symbol: LTA
Name: lymphotoxin alpha
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LTAaffects expressionEXP 6480464CTDAcetaminophen affects the expression of LTA mRNAPMID:31059760
LTAaffects response to substanceEXP 6480464CTDLTA polymorphism affects the susceptibility to AcetaminophenPMID:9696492
LTAmultiple interactionsEXP 6480464CTD[Acetaminophen co-treated with Lipopolysaccharides] affects the expression of LTA mRNAPMID:31059760
LTAincreases expressionISOLta (Mus musculus)6480464CTDAcetaminophen results in increased expression of LTA mRNAPMID:12540782
LTAmultiple interactionsISOLta (Mus musculus)6480464CTDO(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of LTA mRNA]PMID:12540782
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