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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320024
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1e1
Name: aldo-keto reductase family 1, member E1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1e1affects expressionEXP 6480464CTDAcetaminophen affects the expression of AKR1E1 mRNA

PMID:17562736
Akr1e1multiple interactionsEXP 6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of AKR1E1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of AKR1E1 mRNA]

PMID:17585979
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.