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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307383
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc27a4
Name: solute carrier family 27 member 4
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc27a4increases expressionEXP 6480464CTDAcetaminophen results in increased expression of SLC27A4 mRNAPMID:33387578
Slc27a4decreases expressionISOSLC27A4 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of SLC27A4 mRNAPMID:21420995
Slc27a4increases expressionISOSLC27A4 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of SLC27A4 mRNAPMID:29067470
Slc27a4multiple interactionsISOSlc27a4 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of SLC27A4 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC27A4 mRNA]PMID:17585979
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