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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305839
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arih2
Name: ariadne RBR E3 ubiquitin protein ligase 2
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arih2affects expressionISOArih2 (Mus musculus)6480464CTDAcetaminophen affects the expression of ARIH2 mRNAPMID:17562736
Arih2increases expressionISOARIH2 (Homo sapiens)6480464CTDAcetaminophen results in increased expression of ARIH2 mRNAPMID:29067470
Arih2multiple interactionsISOArih2 (Mus musculus)6480464CTD[CTH gene mutant form results in increased susceptibility to Acetaminophen] which affects the expression of ARIH2 proteinPMID:25499718
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