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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10997
Species: Mus musculus
RGD Object: Gene
Symbol: Nos3
Name: nitric oxide synthase 3, endothelial cell
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos3affects expressionEXP 6480464CTDAcetaminophen affects the expression of NOS3 mRNAPMID:17562736
Nos3increases expressionEXP 6480464CTDAcetaminophen results in increased expression of NOS3 proteinPMID:16565415
Nos3multiple interactionsEXP 6480464CTDSemaxinib inhibits the reaction [Acetaminophen results in increased expression of NOS3 protein]PMID:16565415
Nos3decreases expressionISONos3 (Rattus norvegicus)6480464CTDAcetaminophen results in decreased expression of NOS3 mRNAPMID:16172162
Nos3multiple interactionsISONos3 (Rattus norvegicus)6480464CTDAcetaminophen inhibits the reaction [Arsenic results in decreased expression of NOS3 mRNA]PMID:22120977
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