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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10297
Species: Mus musculus
RGD Object: Gene
Symbol: Cbs
Name: cystathionine beta-synthase
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cbsaffects expressionEXP 6480464CTDAcetaminophen affects the expression of CBS mRNAPMID:17562736
Cbsincreases expressionEXP 6480464CTDAcetaminophen results in increased expression of CBS mRNAPMID:25499718
Cbsincreases response to substanceEXP 6480464CTDCBS gene mutant form results in increased susceptibility to AcetaminophenPMID:25499718
Cbsmultiple interactionsEXP 6480464CTD[CBS gene mutant form results in increased susceptibility to Acetaminophen] which results in increased expression of GPT proteinPMID:25499718
Cbsdecreases expressionISOCBS (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of CBS mRNAPMID:22230336
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